The nuclear membrane is a double membrane structure that encloses the nucleus, separating it from the cytoplasm

It consists of two concentric membranes each composed of a lipid bilayer. separated from each other by a narrow perinuclear cisterna.

Outer membrane: Continuous with the endoplasmic reticulum (ER) and may have ribosomes attached.

Inner membrane: Associated with nuclear lamina (a network of proteins providing structural support).

Nuclear pores: Large complexes allowing selective exchange of molecules (e.g., RNA, proteins) between the nucleus and cytoplasm.

 

 

 

The inner membrane is associated with of intermediate filaments called nuclear lamina, which is made of the protein lamin.

The lamina acts as a site of attachment for chromosomes that play an important role in mitosis and in meiosis.

In between these two membranes is a space called perinuclear space. The luminal space within the double-layered nuclear membrane is continuous at points with the endoplasmic reticulum, a membrane-enclosed organelle (continuous with the outer nuclear membrane) to which are attached ribosomes (em2) executing translation of genetic coding into polypeptides and newly synthesized proteins.

These membranes fuse at intervals, forming openings called nuclear pores in the nuclear envelope

The nuclear pore complex.
The nuclear pore complex.
(From by Alberts B, Bray D, Lewis Jet al. Molecular Biology of the Cell. 3rd ed. New York, NY: Garland Science; 1994